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Laboratories using microarrays to study gene regulation by examining DNA methylation patterns or transcription factors generally process large numbers of samples which places a burden on manual methods of preparing samples and setting up and processing microarrays. Also, continuing changes in the format, content and cost of specialty microarrays for these types of studies from the various suppliers leads laboratories to change array platforms and their associated workflows frequently. SciGene instruments are “platform agnostic” and automate and simplify the complex manual steps used with commonly used microarray based assays from sample preparation through slide processing for improved data quality and lower cost. |
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TechnologySciGene’s family of instruments work together to automate the workflow used in DNA methylation and CHiP-CHip assays from sample isolation, amplification and labeling through array hybridization and post-hybridization processing. SciGene instruments can be used with any slide based microarray including those from Agilent, Illumina, Roche NimbleGen and others. The ArrayPrep™ Target Preparation System is a reagent handling and incubation instrument specially designed for purifying, labeling and loading labeled targets onto microarrays. The Mai Tai® Hybridization System accommodates robotic sample loading and applies bubble mixing technology during incubation of multiple slides. The Little Dipper® Processor with NoZone® Workspace automates the washing and drying of microarrays in an ozone-safe environment presenting slides ready for scanning. |
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Automating the Microarray Workflow
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