Overview |
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The current manual methods used to run aCGH based genetic tests are complex and require a completely new set of skills for personnel in the cytogenetics laboratory. The successful adoption of aCGH technology by genetic testing laboratories will require new “operator friendly” automation tools that will simplify and streamline the workflow used for microarray based tests. SciGene has automated the workflow for aCGH based genetic tests by simplifying the process used by lab personnel, making patient tests more reliable at a lower cost. |
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TechnologySciGene’s family of instruments work together to automate the workflow used in aCGH-based tests from sample isolation and labeling through array hybridization and post-hybridization processing. The instruments are platform “agnostic” and can be used with all commercial microarrays including those from Agilent, Roche NimbleGen, BlueGnome and others. The ArrayPrep™ Target Preparation System is a reagent handling and incubation instrument specially designed for purifying, labeling and loading DNA derived from patient samples onto microarrays. The Mai Tai® Hybridization System accommodates robotic sample loading and applies bubble mixing technology during incubation of multiple slides. The Little Dipper® Processor with NoZone® Workspace automates the washing and drying of microarrays in an ozone-safe environment presenting slides ready for scanning. |
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Automating the Microarray Workflow
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Case Study |
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— Kyle Sundin, Laboratory Manager |
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Literature
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